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Test for reproductive toxicity
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Tests for systemic toxicity

     ISO10993-11 specifies requirements and gives guidance on procedures to be folllowed in the evaluation of the potential for medical device materials to cause adverse systemic reactions.

Systemic toxicity include:

Acute systemic toxicity,

Chronic systemic toxicity.

Subacute systemic toxicity ,

Subchronic systemic toxicity,

Routes of administration include:

Oral,   Intravenous,  Intraperitoneal,  Implantation,  Intradermal,  Subcutaneous,  Intramuscular

 

 

 

 

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